In my previous article I discussed the pathogenic roles of HIV inserts in the SARS-CoV-2. However, according to an article by DRASTIC collaborator Charles Rixey (The Myth of the Blind Watchmaker), these sequences were also inserted in order to provide a mechanism for antiviral therapies. To frame his argument, Rixey referred to a 2-year old review article by retired virologist William Gallaher (
I don't think that the four proposed HIV inserts have anything to do with fusion inhibitors first developed for HIV and then coronaviruses.
1. Some fusion inhibitors that work for SARS-CoV-2 also work for other coronaviruses that supposedly don't have these HIV inserts.
2. In the 3-D structure of Spike, the proposed HIV inserts are nowhere near the site of action for the fusion inhibitors.
Great article.