Thank you for the information. Since I am not a biochemist I cannot debate this.
You may recall earlier in the article, Gallaher was studying the effect on fusion inhibitors on SARS-1. His basis for doing this was a pre-existing HIV homology in SARS (before the inserts were added). Nevertheless, if these new inserts are nowhere near the site of action of fusion inhibitors you may be correct.
I don't think that the four proposed HIV inserts have anything to do with fusion inhibitors first developed for HIV and then coronaviruses.
1. Some fusion inhibitors that work for SARS-CoV-2 also work for other coronaviruses that supposedly don't have these HIV inserts.
2. In the 3-D structure of Spike, the proposed HIV inserts are nowhere near the site of action for the fusion inhibitors.
Thank you for the information. Since I am not a biochemist I cannot debate this.
You may recall earlier in the article, Gallaher was studying the effect on fusion inhibitors on SARS-1. His basis for doing this was a pre-existing HIV homology in SARS (before the inserts were added). Nevertheless, if these new inserts are nowhere near the site of action of fusion inhibitors you may be correct.
Great article.